Chlamydia Infection In Females

Overview, Causes, & Risk Factors

Chlamydia is a sexually transmitteddisease, or STD, caused by the organism Chlamydiatrachomatis. Sexually transmitted disease refers to any contagiousdisease transmitted from one person to another during sexual contact. In women,the infection usually occurs in the urinary tract, pelvis, or cervix. Thecervix is the opening between the vagina and the uterus.

What is going on in the body?

The organism Chlamydia trachomatis causes chlamydiainfection. It infects the cells and causes a number of changes. The organism isusually passed from one partner to another during sexual intercourse. Aninfection can also be passed from an infected mother to her baby during birth.This can cause eye infections or pneumonia in the infant.

What are the causes and risks of the infection?

The organism that causes a chlamydia infection is usually passedfrom one partner to another during sexual intercourse. Any other intimatecontact of the genitals, mouth, rectal area, or the sharing of sexual toys cantransmit the organism from one individual to another.

Factors that make some women more likely to have a chlamydia infection are as follows:

  • being sexually active and younger than 20 years old
  • having a low socioeconomic status
  • not using barrier methods of contraception, such as condoms
  • having more than one sexual partner
  • using oralcontraceptives
  • having sex with a partner who previously has had a sexually transmitted disease
  • having sex with a male who has a chlamydia infection of the urinarytract
  • Symptoms & Signs

    What are the signs and symptoms of the infection?

    Most chlamydia infections do not cause any symptoms. For this reason, a sexualpartner may be exposed without either partner knowing it. They may pass theorganism to other unsuspecting partners.

    Symptoms of a chlamydia infection of the cervix in a female may include the following:

  • vaginal discharge
  • mild pain and discomfort when urinating
  • abdominal distress, if the infection has spread to the uterus, tubes, or ovaries
  • pain in the upper right of the abdomen, if the liver isinvolved
  • Chlamydia infections of the throat usually cause a sorethroat.

    Chlamydia infections of the rectum can cause the following:

  • rectal pain
  • discharge from the rectum, which may be bloody
  • frequent, painful urges to have a bowel movement
  • Diagnosis & Tests

    How is the infection diagnosed?

    The provider may suspect a chlamydia infection after taking a medical historyand performing an examination. The provider may take a sample of material fromthe infected area to be checked in the laboratory for the organisms that causethe infection. For a cervical infection, this would involve a pelvic examination and a culture ofmaterial from the surface of the cervix. A throat culture may be ordered if a chlamydia infection of thethroat is suspected.

    Prevention & Expectations

    What can be done to prevent the infection?

    Several safer sex practices can help prevent the spread ofchlamydia infection. Malecondoms and femalecondoms provide some protection. Single partner relationships aresafer than sexual interaction with multiple partners.

    Any new partners should be asked about their sexual history and should betested for sexually transmitteddisease. Sexual contact should be postponed until the tests show noinfection in the partner.

    Finally, a screening for chlamydia can be done in combination with a routine annualPapsmear and pelvic exam.

    What are the long-term effects of the infection?

    Chlamydia infections in females are strongly associated with thedevelopment of cervicaldysplasia, or abnormal cells in the cervix, and cancer of the cervix.

    It is important to treat chlamydia infections to prevent scarring of thefallopian tubes, which connect the ovaries to the uterus. Severe or untreatedchlamydia infections can cause serious complications such as the following:

  • pelvic inflammatory disease, or PID, which involves a widespread infection ofpelvic organs
  • chronic pelvicpain
  • pelvic adhesions, or bands of tissue that cause scarring
  • infertility, or theinability to conceive a child
  • ectopic pregnancy, in which the fertilized eggimplants outside of the uterus
  • premature labor and premature delivery, if a woman is infected duringpregnancy
  • postpartum endometritis, an infection of the uterine lining that occursafter a woman has given birth
  • proctitis, or rectal infection
  • What are the risks to others?

    Chlamydia infections are highly contagious and can be passedthrough sexual intercourse and other intimate contact. A woman who is pregnantcan pass the chlamydia infection to her baby during delivery. The baby maythen develop an eye infection or pneumonia.

    Treatment & Monitoring

    What are the treatments for the infection?

    Taking antibiotics usually cures the infection. Normal healing may still leavesome scar tissue. Sexual partners should also be treated. Sometimes acombination of antibiotics is used for 7 to 10 days. Antibiotics used to treatchlamydia infections include azithromycin, doxycycline, ofloxacin,sulfisoxazole, and erythromycin.

    For severe infections that spread to the abdomen, antibiotics are injected intoa vein. This procedure is done in the hospital. It is important to note that having the infectiondoes not make one immune to it. Anyone can be infected repeatedly.

    What are the side effects of the treatments?

    Antibiotics may cause stomach upset, rash, or allergic reactions.

    What happens after treatment for the infection?

    Antibiotic treatment usually works, but there may still be scarring of thewoman’s reproductive organs. Someone who does not finish taking the entirecourse of antibiotics can be reinfected. Reinfection may also occur unless allsexual partners are treated. In some cases, chlamydia infections do not clearup. This can be due to organisms that are resistant to antibiotics.

    How is the infection monitored?

    After a course of antibiotics has been taken successfully, the healthcareprovider may repeat the culture of material from the infected area. If the testis positive, it usually means reinfection has occurred. This is particularlylikely if a sexual partner has not been treated or did not complete treatment.

    Being screened for chlamydia every year, or any time there is a new sexualpartner, is a good practice. Any new or worsening symptoms should be reportedto the healthcare provider.

    Article type: xmedgeneral